A Multi-Center Clinical Trial To Evaluate Azidothymidine (AZT) in the Treatment of Human Immunodeficiency Virus (HIV) Infection in Patients With AIDS Post First Episode PCP

Inclusion Criteria Concurrent Medication: Allowed: * All concomitant medication to minimum and record. * Any approved medications can be used to treat an opportunistic infection. * Dapsone may be used for Pneumocystis carinii pneumonia (PCP). * Pyrimethamine - sulfadoxine may be used for toxoplasmosis. * Ganciclovir for cytomegalovirus may be used for maintenance only. * Prophylactic therapy for PCP. Concurrent Treatment: Allowed: * Local, limited radiation therapy to isolated Kaposi's sarcoma lesions provided total area is \< 5 x 5 cm and a 6-MeV electron beam or 90 kV x-ray = or \< 3000 rads total is used. Patients must have: * HIV seropositivity as confirmed by any federally licensed ELISA test kit. * Allowed: * Malignancy in past which has been in complete remission for 1 year without therapy. Exclusion Criteria Co-existing Condition: Patients with active opportunistic infections will be excluded. Concurrent Medication: Excluded: * Aspirin on a regular basis or beyond 72 hours without contacting investigator. * Cimetidine. * Flurazepam. * Indomethacin. * Ranitidine. * Probenecid. Patients with the following are excluded: * Status post-Pneumocystis carinii pneumonia with symptomatic visceral Kaposi's sarcoma (KS) or progression of KS within the month prior to study entry. * Other concurrent neoplasms other than basal cell carcinoma of the skin. * Requiring blood transfusions \> once per month. Last transfusion cannot have been given within 7 days of entry. * Active substance abuse. Unwilling to sign informed consent or to be followed at medical center where enrolled for duration of study and follow-up if necessary. Prior Medication: Excluded within 2 weeks of study entry: * Treatment for acute Pneumocystis carinii pneumonia (PCP). * Excluded within 30 days of study entry: * Other antiretroviral agents, immunomodulating agents, or corticosteroids. Prior Treatment: Excluded within 30 days of study entry: * Radiation therapy or cytotoxic chemotherapy for Kaposi's sarcoma. Required: * Patients must be at least 2 weeks post- therapy status for acute Pneumocystis carinii pneumonia (PCP).