The Efficacy of a Standardized Acupuncture Regimen and Amitriptyline Compared With Placebo as a Treatment for Pain Caused by Peripheral Neuropathy in HIV-Infected Patients

Inclusion Criteria Concurrent Medication: Allowed: * Antiretroviral therapy. * Nonsystemic treatment of Kaposi's sarcoma. * Maintenance with an existing regimen of analgesic medication or herbal treatment. Concurrent Treatment: Required: * Acupuncture. Patients must have: * HIV infection. * Lower extremity peripheral neuropathy secondary to HIV infection. * Pain for at least 2 weeks prior to study entry. * Life expectancy of at least 6 months. NOTE: * Co-enrollment in other experimental protocols is permitted as long as dual participation is allowed in those protocols. Prior Medication: Allowed: * Antiretroviral therapy. Exclusion Criteria Co-existing Condition: Patients with the following symptoms or conditions are excluded: * Known allergy to amitriptyline (not applicable for patients at sites using an acupuncture only study design). * EKG indicating malignant arrhythmia or cardiac conduction disturbances (not applicable for patients at sites using an acupuncture only study design). * Prison incarceration. Concurrent Medication: Excluded: * Active treatment for an acute opportunistic infection or malignancy (nonsystemic treatment of Kaposi's sarcoma is permitted). * Other tricyclic antidepressants. * MAO inhibitors. Patients with the following prior conditions are excluded (not applicable for patients at sites using an acupuncture only study design): * History of cardiac disease. * History of seizure disorder. Prior Medication: Excluded within 2 weeks prior to study entry: * MAO inhibitors. * Tricyclic antidepressants.