The Connection Between Areas in the Brain of Blind Patients

N/ACompletedNCT00001926

National Institute of Neurological Disorders and Stroke (NINDS)45 enrolled

Overview

The purpose of this study is to test the belief that specific areas of the brain are connected differently in blind patients than patients with sight. In addition, the study will examine the different anatomical connections between brain areas of patients who became blind early in life versus patients who became blind later.

The purpose of this protocol is to test the hypothesis that the anatomical connectivity of occipital and somatosensory areas in early blind subjects differs from that in subjects who became blind later in life and from that in sighted volunteers.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Blindness Brain Mapping Healthy

Interventions

O15DRUG

Cadwell rTMSDEVICE

Eligibility

Sex: ALLHealthy volunteers:

Medical Language ↔ Plain English

INCLUSION CRITERIA: Subjects with late blindness. Subjects with early blindness. Sighted volunteers. Age between 18 and 65 years. EXCLUSION CRITERIA: Subjects with personal or family history of seizures or other neurological or demyelinating disorders. Pregnant women tested after urine pregnancy test. Subjects with metal in the cranium except mouth. Subjects with intracardiac lines and implanted medication pumps. Subjects with increased intracranial pressure as evaluated by clinical means. Subjects with cardiac pacemakers. Intake or neuroleptics. Subjects with blindness secondary to degenerative CNS diseases.

Locations (1)

National Institute of Neurological Disorders and Stroke (NINDS)

Bethesda, Maryland, United States

Data from ClinicalTrials.gov

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