Evaluation of Amphotericin B in the Treatment of Biopsy Proven Candida Esophagitis in Immunocompromised Patients

Exclusion Criteria Co-existing Condition: Patients with histological or clinical (skin rash, cotton wool exudates, Candida endophthalmitis, etc.) evidence of disseminated candidiasis are excluded. Concurrent Medication: Excluded: * Systemic administration of amphotericin B for a proven or suspected systemic fungal infection. Patients with the following are excluded: * Documented Candida fungemia. * Histological or clinical (skin rash, cotton wool exudates, Candida endophthalmitis, etc.) evidence of disseminated candidiasis. * Systemic administration of amphotericin B for a proven or suspected systemic fungal infection. * Patient refusal to enter study. Patient must be an immunosuppressed host, with biopsy-proven Candida esophagitis. * Patients with polymicrobial esophagitis will be included as long as Candida esophagitis is documented by esophageal biopsy. * Informed consent must be signed and obtained.