Dapsone 100 Mg Versus 50 as Primary Prophylaxis for Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS-Related Complex (ARC)

Inclusion Criteria The patient must have HIV positive antibody test and presence of oral thrush or hairy leukoplakia. * Patient must be willing and able to sign informed consent. Exclusion Criteria Co-existing Condition: Patients with the following are excluded: * Prior Pneumocystis carinii pneumonia (PCP) or AIDS-defining condition. * Prophylaxis for PCP in preceding 3 months. * Absence of detectable glucose-6-phosphate dehydrogenase (G6PD) activity. * Prior type I hypersensitivity (anaphylaxis, urticaria, angioedema) or exfoliative dermatitis during treatment with dapsone. * History of poor compliance. Concurrent Medication: Excluded: * Zidovudine (AZT). Patients with the following are excluded: * Prior Pneumocystis carinii pneumonia (PCP) or AIDS-defining condition. * Prophylaxis for PCP in preceding 3 months. * Absence of detectable glucose-6-phosphate dehydrogenase (G6PD) activity. * Concurrent or prior therapy with zidovudine (AZT). * Prior type I hypersensitivity (anaphylaxis, urticaria, angioedema) or exfoliative dermatitis during treatment with dapsone. * History of poor compliance. Prior Medication: Excluded: * Zidovudine (AZT).