A Three-Arm Comparative Trial for the Treatment of MAC Bacteremia in AIDS: A Clarithromycin/Ethambutol Regimen Containing Rifabutin (450 Mg) or Rifabutin (300 Mg) or Placebo

Inclusion Criteria Concurrent Medication: Allowed: * Isoniazid for TB prophylaxis ONLY. Patients must have: * HIV infection. * MAC infection. * Life expectancy of at least 16 weeks. Exclusion Criteria Co-existing Condition: Patients with the following symptoms or conditions are excluded: * Perceived unreliability or unavailability for frequent monitoring. Concurrent Medication: Excluded: * Antimycobacterial drugs other than the study drugs. * Carbamazepine. * Terfenadine. * Theophylline. Patients with the following prior condition are excluded: History of hypersensitivity to rifabutin, rifampin, erythromycin, clarithromycin, azithromycin, or ethambutol. Prior Medication: Excluded within 7 days prior to study entry: * Rifabutin. * Rifampin. * Ethionamide. * Cycloserine. * Clofazimine. * Ethambutol. * Amikacin. * Ciprofloxacin. * Ofloxacin. * Sparfloxacin. * Azithromycin. * Clarithromycin. * Pyrazinamide. Excluded within 14 days prior to study entry: * Carbamazepine. * Terfenadine. * Theophylline.