A Study of Fluconazole in the Prevention of Fungal Infections in HIV-Infected Patients Living in Areas Where Fungal Infections Are Common

Inclusion Criteria Patients must have: * Documented HIV infection. * CD4 count \< 250 cells/mm3. * No active coccidioidomycosis or other fungal disease requiring systemic antifungal therapy. * Residence in area considered to be endemic for Coccidioides immitis. * Consent of parent or guardian if under legal age of consent. Exclusion Criteria Co-existing Condition: Patients with the following symptoms or conditions are excluded: * Unable to take oral medication. * Positive serum cryptococcal antigen. Concurrent Medication: Excluded: * Systemic antifungal therapy. Patients with the following prior conditions are excluded: History of hypersensitivity to azole or imidazole compounds. Prior Medication: Excluded: * Systemic antifungal agents within 2 weeks prior to study entry.