A Study of Fluconazole in the Treatment of Fungal Infections of the Throat in Patients With Weakened Immune Systems

Inclusion Criteria Patients must have: * AIDS or other immunocompromising condition. * Candidal esophagitis. * Life expectancy of at least 2 months. Exclusion Criteria Co-existing Condition: Patients with the following symptoms or conditions are excluded: * Evidence of non-candidal systemic fungal infection. * Abnormalities that may preclude esophagoscopy or endoscopy. * Unable to tolerate fluconazole. * Unable to give informed consent. * Enrollment in other experimental trials of approved or non-approved drugs or systemic compounds (unless approved by the Pfizer Clinical Monitor). * Other condition that would make patient unsuitable for enrollment. Concurrent Medication: Excluded: * Concomitant oral or topical antifungal agent. * Other experimental medications. Patients with the following prior condition are excluded: History of allergy to imidazoles or azoles. Prior Medication: Excluded: * Any oral or topical antifungal therapy within the past 3 days. Active use of illicit or illegal drugs.