To compare the antiviral effect of stavudine ( d4T ) versus placebo in patients with evidence of recent HIV infection. Also, to compare the immunologic effects and effects on quality of life of d4T in these patients.
Patients receive d4T or placebo every 12 hours for 4 weeks, after which dose decreases (or placebo) every 12 hours. Treatment continues for at least 48 weeks.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
40
San Diego Naval Hosp
San Diego, California, United States
Naval Med Ctr
Portsmouth, Virginia, United States
Northwest Med Ctr
Seattle, Washington, United States
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.