The Safety and Effectiveness of HBY 097 Used With or Without AZT in HIV-Infected Patients Who Have Mild or No Symptoms

Inclusion Criteria Concurrent Medication: Allowed: * Treatment for opportunistic infection that develops on study. Recommended: * PCP prophylaxis if CD4 count falls below 200 cells/mm3. Patients must have: * HIV infection. * CD4 count 200 - 500 cells/mm3. * HIV-1 RNA PCR value of 10000 copies/ml or higher. * Asymptomatic or mildly symptomatic disease. * No past or current AIDS-defining event. * Consent of parent or guardian if less than legal age of consent. Exclusion Criteria Co-existing Condition: Patients with the following symptoms or conditions are excluded: * Endocrine, hepatic, renal, or gastrointestinal disease. * Cardiovascular conduction disease. * Concomitant medical illness that may complicate study conduct or interpretation of results. * Other factors that may interfere with patient compliance. Concurrent Medication: Excluded: * Antiretroviral agents other than study drugs. * Oral contraceptives. * Cytotoxic chemotherapy. * Immunomodulators. * Antiproliferative agents. * Corticosteroids. * Anabolic steroids. * Estrogens. * Quinoxaline derivatives. Concurrent Treatment: Excluded: * Radiation therapy. Patients with the following prior conditions are excluded: * History of hypersensitivity to quinoxaline derivatives or intolerance to AZT. * History of cardiovascular conduction disease. * Prior participation in this study or any study using HBY 097. * Recent use of a drug that interferes with drug metabolism, absorption, distribution, or excretion. * History of thyroid disease. Prior Medication: Excluded at any time: Prior non-nucleoside reverse transcriptase inhibitors. Excluded within 30 days prior to study entry: * Any antiretroviral therapy. * Oral contraceptives. * Immunomodulating agents such as systemic corticosteroids, interleukins, or interferons. * Cytotoxic chemotherapeutic agents. * Other investigational drugs. Excluded within 6 months prior to study entry: Immunotherapeutic vaccine. Prior Treatment: Excluded within 30 days prior to study entry: * Radiation therapy. * An experimental device. Current ethanol or illicit drug abuse.