Ultraviolet Light Therapy for Systemic Lupus Erythematosus

National Center for Research Resources (NCRR)20 enrolled

Overview

OBJECTIVES: I. Evaluate the mechanisms of ultraviolet A-1 light therapy in patients with systemic lupus erythematosus and normal controls.

PROTOCOL OUTLINE: Treatment with ultraviolet A-1 light is administered 5 days a week for 6 weeks, at the lowest dose or frequency required to maintain a response. The dose and frequency are progressively decreased over the next 9 weeks.

Study Type

INTERVENTIONAL

Purpose

TREATMENT

Enrollment

Conditions

Systemic Lupus Erythematosus

Interventions

ultraviolet A-1 light treatmentPROCEDURE

Eligibility

Sex: ALLMin age: 15 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

PROTOCOL ENTRY CRITERIA: --Disease Characteristics-- Patients ages 15 to 70 with symptomatic systemic lupus erythematosus meeting American Rheumatism Association criteria and normal controls --Prior/Concurrent Therapy-- No requirement for tetracycline or other photosensitizing drugs

Locations (2)

General Clinical Research Center and Charity Hospital (University of Louisiana)

New Orleans, Louisiana, United States

RECRUITING

Alton Ochsner Medical Foundation Hospital

New Orleans, Louisiana, United States

RECRUITING

Data from ClinicalTrials.gov

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