Study of the Regulation of Parathyroid Hormone Secretion in Pseudohypoparathyroidism

National Center for Research Resources (NCRR)20 enrolled

Overview

OBJECTIVES: Determine the relationship between serum calcium concentrations and parathyroid hormone secretion in patients with pseudohypoparathyroidism.

PROTOCOL OUTLINE: Patients are tested for parathyroid hormone response following sequential graded intravenous infusions of sodium citrate and calcium gluconate. Assays include ionized calcium and intact parathyroid hormone.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Pseudohypoparathyroidism

Eligibility

Sex: ALLMin age: 12 Years

Medical Language ↔ Plain English

PROTOCOL ENTRY CRITERIA: --Disease Characteristics-- Pseudohypoparathyroidism, i.e.: Renal resistance to parathyroid hormone OR Albright hereditary osteodystrophy No other illness unless related to pseudohypoparathyroidism No pregnant women

Data from ClinicalTrials.gov

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