A Multicenter, Prospective, Randomized, Double-Blind Clinical Trial Comparing Itraconazole Oral Solution in Cyclodextrin to Placebo in the Treatment of Aspergilloma

Inclusion Criteria: You may be eligible for this study if you: * Are 18 years of age or older. * Have been diagnosed with aspergilloma within the last month. * Have (or have a history of) at least one of the following: 1. positive test for Aspergillus species. 2. presence of antibodies to Aspergillus. * Are willing to participate in the study for 2 full years. * Are female and not pregnant. * Are not breast-feeding. * Agree to use barrier methods of birth control / contraception during the study and for 30 days after. Exclusion Criteria: You will not be eligible for this study if you: * Have a history of allergy to triazole or imidazole drugs. * Are unable to take oral medication. * Are not expected to live for more than a month. * Have had a lung biopsy indicating Aspergillus infection. * Have had radiation therapy within the last 6 months. * Require treatment with certain medications. * Received amphotericin, amphotericin lipid formulation, fluconazole, or itraconazole in the two weeks prior to study entry. * Received chemotherapy within the last 6 months.