Diagnostic Pilot Study of Dual Energy Absorptiometry in the Detection of Osteopenia or Osteoporosis in Patients With Thalassemia Major

National Center for Research Resources (NCRR)35 enrolled

Overview

OBJECTIVES: I. Determine the frequency and severity of osteopenia and osteoporosis in patients with thalassemia major who undergo dual energy x-ray absorptiometry, and correlate these findings with other relevant endocrinologic measurements.

PROTOCOL OUTLINE: Patients undergo dual energy x-ray absorptiometry for bone density measurements, height (sitting and standing) and weight measurements, comprehensive endocrinologic examination, and assessment of the severity of iron overload at baseline, and then at years 1 and 2.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Osteoporosis Thalassemia Major Osteopenia

Eligibility

Sex: ALLMin age: 6 Years

Medical Language ↔ Plain English

* Diagnosis of thalassemia major with iron overload * Not pregnant * Negative pregnancy test

Data from ClinicalTrials.gov

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