Protection Against Benzene Toxicity

National Institute of Environmental Health Sciences (NIEHS)

Overview

We are investigating the role of an enzyme (NQO1) in protection against the bone marrow toxicity of the occupational and environmental toxicant benzene. All of the proposed studies involve use of human bone marrow cells in-vitro to define mechanisms of NQO1-mediated protection. Cells are obtained from healthy volunteers and protocols have undergone IRB review and approval.

Study Type

OBSERVATIONAL

Conditions

Leukemia Aplastic Anemia

Eligibility

Sex: ALLMin age: 21 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Healthy adult volunteers with blood counts in normal ranges and without evidence of hepatitis or HIV infection.

Locations (1)

University of Colorado Health Sciences Center

Denver, Colorado, United States

Data from ClinicalTrials.gov

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