Prepulse Inhibition of Startle in Cocaine Dependence - 7

National Institute on Drug Abuse (NIDA)

Overview

The purpose of this study is to assess the effects of chronic cocaine use on the acoustic startle response and on gating of this response in humans.

The objective of this study is to assess the effects of chronic cocaine use on the acoustic startle response and on gating of this response in humans.

Study Type

INTERVENTIONAL

Purpose

DIAGNOSTIC

Masking

DOUBLE

Conditions

Interventions

AmantadineDRUG

Eligibility

Sex: MALEMin age: 18 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: Cocaine dependence. Male. Right handed. Negative urine for cocaine Exclusion Criteria: Positive urine for cocaine. History of head trauma. Significant medical disease.

Locations (1)

New York MDRU

New York, New York, United States

Outcomes

Primary Outcomes

Percent prepulse inhibition

Cocaine assessment

Data from ClinicalTrials.gov

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