Reserpine for the Treatment of Cocaine Dependence - 1

National Institute on Drug Abuse (NIDA)140 enrolled

Overview

The purpose of this study is to assess the efficacy and safety of reserpine for the treatment of cocaine dependence.

To assess the efficacy and safety of reserpine in reducing cocaine use in subjects with cocaine dependence. This is a double-blind, placebo-controlled, parallel-group design with a 2 week baseline period.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

140

Conditions

Interventions

ReserpineDRUG

Eligibility

Sex: ALLMin age: 18 YearsMax age: 99 Years

Medical Language ↔ Plain English

Inclusion Criteria: Be at least 18 yrs of age; DSM-4 diagnosis of cocaine dependence; treatment seeking individuals; have the ability to understand and provide written informed consent; females of child bearing potential using appropriate birth control method Exclusion Criteria: Additional criteria available during screening at the site.

Locations (3)

Boston University Medical Center

Boston, Massachusetts, United States

Cincinnati VA Medical Center

Cincinnati, Ohio, United States

Dayton VA Medical Center

Dayton, Ohio, United States

Outcomes

Primary Outcomes

Cocaine use

Addiction severity

Cocaine withdrawal

Adverse events

Clinical improvement

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.