Study of TLK199 HCl Liposomes for Injection in Myelodysplastic Syndrome

Inclusion Criteria: * Histologically or cytologically confirmed diagnosis of MDS * Adequate liver and kidney function * Ineligible for, or refusing, allogeneic bone marrow transplant * At least 18 years of age * Discontinuation of growth factors (e.g., G- CSF) at least 2 weeks prior to study entry Exclusion Criteria: * Failure to recover from any prior surgery, or any major surgery within 4 weeks of study entry * Pregnant or lactating women * History of allergy to eggs * Other investigational drugs within 14 days of study entry * Chemotherapy, radiotherapy or immunotherapy within 14 days of study entry * Concomitant steroids or hormones for the treatment of neoplasms