rhTPO Mobilized Auto Cryo Platelets For GYN Patients Receiving Carboplatin

INCLUSION CRITERIA: * Patients with gynecologic malignancy for whom treatment with carboplatin is indicated. * Age \>/= 15 years. * Adequate hematologic, renal, and hepatic functions. * Life expectancy \>/- 3 months. Karnofsky Performance Status \>/= 80. * Signed informed consent form. EXCLUSION CRITERIA: * Patients with rapidly progressive disease. * Pregnant or lactating women. * Patients with comorbid condition which renders patients at high risk of treatment complication. * History of CNS metastasis. * Patients with significant cardiac disease (NYHA Class III or IV), dysrhythmia, or recent history of MI or ischemia, transient ischemic attack or CVA within the 6 months of study entry. * Prior chemotherapy, immunotherapy, any experimental drug within 4 weeks, use of myeloid (G-CSF or GM-CSF) growth factors within 2 weeks or erythropoietin within 4 weeks. * Use of any nitrosourea (BCNU, CCNU) or mitomycin - C within 6 weeks. * Prior surgery or RT within 2 wks of study entry. * Patients with history of prior high dose chemotherapy with stem cell transplant or with history of prolonged thrombocytopenia (\> 2 weeks). * History of leukemia. * History of any platelet disorders including ITP, TTP or bleeding disorders. * History of \> 3 prior chemotherapy regimens (all platinum regimens will be counted as 1 regimen). * Demonstrated lack of response to platinum-based therapy.