Phase 2 Study of TLK286 in Platinum Resistant Advanced Epithelial Ovarian Cancer

Inclusion Criteria * Histologic diagnosis of ovarian cancer * Recurrent or persistent disease following primary therapy * Measurable disease * Prior treatment with at least one but no more than three prior chemotherapy regimens * Resistant or refractory to platinum-based chemotherapy * At least 18 years of age * Good performance status (ECOG 0 to 1) * Adequate liver, renal and bone marrow function Exclusion criteria * Pregnant or currently breast feeding * Treatment with chemotherapy or immunotherapy within four weeks * Prior radiation to the whole pelvis