Olanzapine Versus Placebo in the Treatment of Mania in Adolescents With Bipolar I Disorder

Inclusion Criteria: * Male or female patients, 13 to 17 years of age who must not yet have reached their 18th birthday prior to Visit 1, when informed consent is obtained. * Patients must have a diagnosis of bipolar I disorder and currently display an acute mania or mixed episode. * Both the patient and the patient's parent/authorized legal representative must understand the nature of the study and must sign a document granting consent. * Female patients of child-bearing potential must test negative for pregnancy at the time of enrollment based on a serum pregnancy test. Exclusion Criteria: * Female patients who are either pregnant or nursing. * Current diagnosis of schizophrenia, schizophreniform disorder, or schizoaffective disorder. * Patient with acute or unstable medical conditions, such that intensive care unit hospitalization for the disease is anticipated within 6 months. * Patients who have previously not responded to an adequate dose and/or duration of olanzapine treatment. * Patients who have been judged clinically to be serious suicidal risks.