Capravirine (AG1549) in Combination With Viracept and Two NRTIs in HIV Infected Patients Who Failed an Initial NNRTI Containing Regimen

Inclusion Criteria: * Male or female at least 18 years old * HIV RNA level \>1000 copies/mL at screening * CD4 \>50 cells/uL at screening * Patient is currently taking a regimen that includes an NNRTI plus 2 NRTIs for at least 28 days and is currently failing this regimen * Patient has adequate hematology tests (absolute neutrophil count \>1000/uL, Platelets\>75,000uL, hemoglobin 9g/L) * Patient has adequate renal function (serum creatinine of \<1.5 upper limit of normal) * Patient has adequate liver function (AST, ALT, and bilirubin \< 2.5 upper limit of normal) Exclusion Criteria: * Previous use of protease inhibitors (except if patient has short duration of PI and was switched for tolerability reasons when viral load was \<50 copies) This exception does not include Viracept * Women who are pregnant or lactating