This study will compare the effectiveness of Problem Solving Therapy and Brief Supportive Therapy in treating elderly patients with major depression and thought problems.
Patients who suffer from a combination of major depression and executive dysfunction symptoms often respond poorly to treatment with antidepressants. It is important, therefore, to find effective alternative therapies to treat these symptoms. Patients are randomly assigned to receive 12 sessions (1 session/week for 12 weeks) of either PST or BST. Following treatment, patients are followed for 6 months to determine functional and clinical outcomes. Depression scales, disability scales, and scales that measure problem solving skills are used to assess patients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
221
A 12 week cognitive behavioral intervention for depression that teaches patients a structured approach to solving social problems.
A 12 week intervention for depression that focuses on supporting patients attempts to cope with depression.
University of California at San Francisco
San Francisco, California, United States
Weill Medical College of Cornell University
White Plains, New York, United States
Hamilton Rating Scale for Depression
Time frame: Measured at screening, weeks 1 through 12, and week 36
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