This study was designed to examine the effectiveness of a breath-operated albuterol inhaler in asthma patients who have difficulty using their standard "press-and-breathe" inhaler.
This was a single-center, randomized, open-label, active-controlled, 2-period, 2-sequence, single dose-dose, crossover comparison of the ability of Albuterol BOI-HFA to produce bronchodilation relative to that produced by to albuterol MDI-HFA in at least 12 asthmatics with poor inhaler coordinating ability.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
14
Albuterol HFA breath operated inhaler, 90 mcg/sprau
Albuterol HFA multi-dose inhaler
National Jewish Medical and Research Ceter
Denver, Colorado, United States
Percent change in SGaw (A measure of the change in specific airway conductance - how hard it is to get air into the lungs)
Time frame: Pre-dose and +120 minutes
The area-under-the-effect curve of change in SGaw from basline over time
Time frame: Pre-dose and +120 minutes
The maximum increase in SGaw from baseline over two hours
Time frame: Baseline through +120 minutes
Time in hours to the maximum increase in SGaw from baseline
Time frame: Baseline through +120 minutes post-dose
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.