Pomegranate Juice in Treating Patients With Recurrent Prostate Cancer

Inclusion Criteria: * Histologically confirmed adenocarcinoma of the prostate * Must have undergone prior surgery or radiotherapy for the primary tumor * Documented rising prostate-specific antigen (PSA) level, defined by the following criteria: * Absolute level of PSA at least 0.2 ng/mL but less than 5.0 ng/mL * Rising PSA level must be confirmed at least 1 week later * Adequate PSA time points to calculate a PSA doubling time * Gleason score no greater than 7 * Age 18 and over * Performance status ECOG 0-1 * Life expectancy at least 6 months * No other malignancy within the past 5 years except nonmelanoma skin cancer * No other serious concurrent systemic medical disorders that would preclude study compliance * No known allergy to pomegranate juice * More than 4 weeks since prior participation in another experimental study Exclusion Criteria: * nodal involvement * evidence of metastatic disease * prior hormonal therapy * concurrent hormonal therapy for rising PSA levels after initial therapy for prostate cancer * concurrent participation in another experimental study * other concurrent systemic or local therapy for prostate cancer * initiation or discontinuation of any new nutritional or dietary supplements during study participation