This study will evaluate the long-term effectiveness of interpersonal psychotherapy, behavioral weight loss interventions, and guided self help treatments in treating binge eating disorder (BED).
BED is a serious condition that is associated with psychiatric comorbidity, psychosocial impairment, and obesity. Interpersonal psychotherapy (IPT), behavioral weight loss (BWL) interventions, and guided self help (GSH) treatments for BED have been evaluated, but the safest and most effective treatment has not yet been identified. This study will determine which of these three treatments is most effective in treating BED. Participants are stratified by negative affect subtype and are randomly assigned for 6 months to one of three treatment groups: IPT, BWL, or GSH. IPT focuses on current interpersonal problems which are hypothesized to increase negative affect and lead to binge eating. BWL interventions involve the adoption of weight loss inducing behaviors. GSH is a shortened version of cognitive behavioral therapy that focuses directly on eating behavior. IPT and BWL patients have 20 treatment sessions; those receiving GSH have 10 sessions. Assessments are made pre-treatment, post-treatment, and at 6, 12, 18, and 24 months after treatment is complete.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
205
20 sessions of interpersonal therapy were provided over a 6-month period
20 sessions of behavioral weight loss treatment were provided over a 6-month period
10 sessions of guided self help were provided over a 6-month period
W. Stewart Agras
Stanford, California, United States
Washington University School of Medicine
St Louis, Missouri, United States
Rutgers University Eating Disorder Clinic
Piscataway, New Jersey, United States
Binge eating
Rate of binge eating
Time frame: Pre-treatment, 6, 12, and 24-months
Eating disorder psychopathology
Assessed by the Eating Disorder Examination
Time frame: pre-treatment, 6, 12, 24 months
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