ABX-EGF (a Monoclonal Antibody) Given to Patients With Prostate Cancer With or Without Tumor in Other Parts of the Body

Inclusion Criteria: * Male 18 years of age or older * Has tumor tissue available for diagnostics * Failed front line luteinizing hormone-releasing hormone analogue (LHRH) such as leuprolide or goserelin, or failed orchiectomy, as evidenced by disease progression. Patients must continue on a LHRH analogue (unless the patient had an orchiectomy) throughout the course of the study * ECOG score of 0 or 1 Exclusion Criteria: * Any prior chemotherapy for prostate cancer besides hormonal therapy (including no prior EGFr targeting agent) * Prior history of cancer other than prostate carcinoma within the past 5 years that has required treatment or been active (prior basal cell carcinoma is allowed) * Known to be HIV positive * Myocardial infarction within one year prior to entering the study