Pemetrexed Plus Gemcitabine for Patients With Locally Advanced or Metastatic NSCLC Who Have Not Had Previous Chemotherapy.

Inclusion Criteria: * Diagnosis of Non-Small Cell Lung Cancer that can be treated with chemotherapy * Have received no prior chemotherapy for Non-Small Cell Lung Cancer * Have at least one measurable lesion * Have an adequate performance status * Sign an informed consent Exclusion Criteria: * A female who is pregnant or breastfeeding * Treatment with an investigational drug within the last 30 days, previously completed or withdrawn from this study or any other study investigating pemetrexed * Treatment with radiation therapy within the last 1-2 weeks * Brain metastasis that is uncontrolled * Active infection or other serious condition