Oxypurinol Compared With Placebo for Class III-IV NYHA Congestive Heart Failure

Inclusion criteria * 18-85 years old, * Stable NYHA Class III-IV * Hospitalization or ER visits in past 18 months for worsening Heart Failure (or addition of new heart failure medication added to regimen due to lack of stability on current regimen. * EF =\< 40% Exclusion criteria * Any condition (other than CHF) that could limit exercise * Any concurrent disease likely to limit life expectancy. * Participation in another clinical trial * Primary valvular disease, active myocarditis, or an obstructive or restrictive cardio-myopathy * Heart Attack, Stroke, Unstable Angina or Cardiac surgery within previous 3 months