The purpose of this study is to compare the efficacy of Faslodex (fulvestrant) to Aromasin (exemestane) in hormone receptor positive postmenopausal women with advanced breast cancer. Patients will be treated until disease progression or until the investigator has determined that treatment is not in the best interest of the patient, whichever occurs first.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
694
intramuscular injection
oral capsule
Research Site
Birmingham, Alabama, United States
Research Site
Arcadia, California, United States
Research Site
Fountain Valley, California, United States
Research Site
Laverne, California, United States
Research Site
Long Beach, California, United States
Research Site
Time to disease progression (TTP)
Time frame: after 580 Progression events accrued
Objective response rate
Time frame: after 580 Progression events accrued
Overall survival
Time frame: after 580 Progression events accrued
Duration of response
Time frame: after 580 Progression events accrued
Clinical Benefit
Time frame: after 580 Progression events accrued
Quality of Life
Time frame: after 580 Progression events accrued
PK
Time frame: each visit
Safety and tolerability.
Time frame: after 580 Progression events accrued
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Santa Rosa, California, United States
Research Site
Torrington, Connecticut, United States
Research Site
Washington D.C., District of Columbia, United States
Research Site
Boca Raton, Florida, United States
Research Site
Gainesville, Florida, United States
...and 107 more locations