The Effects of Overfeeding on Obesity-Prone (OP) and Obesity-Resistant (OR) Women

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)100 enrolled

Overview

This is a longitudinal cohort study of how the responses to a 3 day period of controlled overfeeding relate to subsequent weight gain. We hypothesize that thin individuals are resistant to weight gain because they respond to periods of overfeeding by increasing fat oxidation, reducing food intake, and increasing physical activity relative to those who gain weight over time.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Obesity Thinness Weight Gain

Eligibility

Sex: ALLMin age: 25 YearsMax age: 35 YearsHealthy volunteers:

Medical Language ↔ Plain English

* Half of the subjects will be women, half will be men, * age 25-35, * a range of BMI's from 19-27, for the 'thin subjects' there should be no 1st degree relatives with a BMI\>30. * Subjects should not engage in planned physical activity more than 3 hrs per week. * For the obesity prone group there should be at least 1 1st degree relative with a BMI\>30.

Locations (1)

University of Colorado Health Sciences Center

Denver, Colorado, United States

Data from ClinicalTrials.gov

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