Pilot Trial of Cognitive and Behavioral Treatment of Compulsive Hoarding Compared to Wait List Control

Boston University Charles River Campus52 enrolled

Overview

This study developed and tested a specialized cognitive and behavioral treatment for the symptoms of hoarding disorder, including excessive acquiring, difficulty discarding items, and extensive clutter in the home.

Compulsive hoarding is characterized by excessive acquisition of possessions, difficulty discarding possessions, and excessive clutter. This condition is resistant to standard pharmacological and psychotherapeutic interventions that have proven effective in treating other obsessive compulsive spectrum disorders. This study aimed to determine the effectiveness of a specialized cognitive behavioral therapy (CBT) designed for treating hoarding symptoms. This study consists of three phases. In Phase 1, pilot data from previous studies were examined to develop an intervention suitable for use in a waitlist trial. In Phase 2, pilot study information were used to develop and test a treatment manual for compulsive hoarding. During this phase, treatment was applied flexibly to allow for variations in treatment duration and choice of techniques. During Phase 3, participants were randomly assigned to 26 weekly sessions of CBT or to a 12-week wait-list control, followed by active treatment for a fixed duration of 26 sessions. Therapist adherence and competence were assessed through audiotaped therapy sessions.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Obsessive-Compulsive Disorder

Interventions

Cognitive Behavioral TreatmentBEHAVIORAL

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion criteria: * Display at least moderately severe hoarding symptoms * Must live within 45 minutes of Boston, MA or Hartford, CT Exclusion criteria: * Ten or more sessions of cognitive behavior therapy for hoarding * Concurrent psychotherapy or medications * Suicidal, psychotic, or other psychiatric symptoms requiring hospitalization * Compulsive buying symptoms that are part of a manic phase of bipolar disorder * Mental retardation, dementia, brain damage, or other cognitive dysfunction that would interfere with the study

Locations (2)

Hartford Hospital, Institute of Living

Hartford, Connecticut, United States

BostonUCRC

Boston, Massachusetts, United States

Outcomes

Primary Outcomes

Saving Inventory-Revised

Self-report questionnaire of hoarding severity; total score range = 0 to 92; higher values indicate more symptoms

Time frame: change from baseline to week 12; change from baseline to week 26

Secondary Outcomes

Hoarding Rating Scale

Interviewer measure with 5 questions to assess hoarding severity; total score range = 0 to 40; higher values indicate more symptoms

Time frame: change from baseline to week 12; change from baseline to week 26

Data from ClinicalTrials.gov

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