Treatment of Adolescent Suicide Attempters (TASA)

New York State Psychiatric Institute120 enrolled

Overview

The purpose of this study is to compare the effects of three types of treatments for depressed teenagers who have attempted suicide.

Suicide is the third leading cause of death in adolescents and is a major public health problem. Depression is the most common diagnosis for adolescent suicide attempts. Little is known about what treatment is best for these adolescents since they are usually excluded from participation in research studies. Participants in this study will be randomly assigned to receive carefully monitored antidepressant medication with routine support and management, cognitive behavioral therapy (CBT), or a combination of antidepressant medication plus CBT.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

120

Conditions

Depression Suicide, Attempted

Interventions

fluoxetineDRUG

sertralineDRUG

citalopramDRUG

escitalopramDRUG

Eligibility

Sex: ALLMin age: 12 YearsMax age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * At least one suicide attempt or interrupted attempt within the past 45 days * Continuously reside with a primary caretaker (parent, legal guardian, foster parent) for at least 6 months that can provide legal consent

Locations (6)

Johns Hopkins University

Baltimore, Maryland, United States

New York University Child Study Center

New York, New York, United States

Columbia University at the New York State Psychiatric Institute

New York, New York, United States

Duke University Medical Center

Durham, North Carolina, United States

Data from ClinicalTrials.gov

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