Study of TLK286 (Telcyta) vs. Gefitinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Telik520 enrolled

Overview

The purpose of this study is to determine if TLK286(Telcyta) is more effective than gefitinib (Iressa) in the treatment of non-small cell lung cancer.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

520

Conditions

Non Small Cell Lung Carcinoma

Interventions

TLK286 (Telcyta) HCl for InjectionDRUG

gefitinib (Iressa)DRUG

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Clinical diagnosis of non-small cell lung cancer * Non-small cell lung cancer that is not curable with surgery, radiation, or combined modality chemoradiation * Failed two prior chemotherapy regimens which must have included platinum * Measurable disease Exclusion Criteria: * Treatment with more than two prior chemotherapy regimens * History of bone marrow transplantation or stem cell support * Pregnant or lactating women * Known history of prior gefitinib therapy * Known history of prior TLK286 therapy

Locations (338)

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.

UAB CCC Clinical Studies Unit

Birmingham, Alabama, United States

Department of Veterans Affairs Medical Center

Birmingham, Alabama, United States

University of Alabama at Birmingham

Birmingham, Alabama, United States

University of Alabama at Birmingham

Birmingham, Alabama, United States

Palo Verde Hematology Oncology

Glendale, Arizona, United States

Little Rock Hematology Oncology Benton

Benton, Arkansas, United States

Highlands Oncology Group

Bentonville, Arkansas, United States

Highlands Oncology Group

Fayetteville, Arkansas, United States

Heritage Physician Group, Oncology

Hot Springs, Arkansas, United States

University of Arkansas for Medical Sciences

Little Rock, Arkansas, United States

...and 328 more locations