Controlled Study of the Use of Quetiapine Fumarate in the Treatment of Patients With Bipolar Depression

Inclusion Criteria: * Provision of informed consent before enrollment and any study-specific procedures. Patients deemed incapable of providing written consent will not be enrolled in this study; outpatient status Exclusion Criteria: * More than 8 mood episodes in the past year from screen (visit 1); * A current Axis I disorder other than bipolar disorder within 6 months of screening; * patients with clinically significant abnormal laboratory findings in the investigator's judgment