The purpose of this study was to examine pharmacological and psychological interventions for smokers over 50.
The overall goals of this line of research were to prevent relapse to cigarette smoking, and to understand the processes related to smoking and relapse. The specific aims of the current study were to test a series of hypotheses about the efficacy and cost-effectiveness of long-term, tailored interventions in chronic, older smokers and the interaction of these interventions with gender and depression. Participants were 50 years or older and smoker 10 or more cigarettes per day. Baseline assessments includes measures of smoking behavior, nicotine dependence, depression diagnosis, demographics and life circumstances and measures of anger, depression and mood disturbance, stress, social support, health status, motivation for changed and drug and alcohol use.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
403
Subjects receive 12 weeks of bupropion treatment and 10 weeks of nicotine replacement.
San Francisco
San Francisco, California, United States
Participants Abstinent From Cigarettes
Primary outcome variable was 7-day point prevalence cigarette abstinence verified biochemically at week 104
Time frame: Two years
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