Monotherapy Study in Patients With Type 2 Diabetes Mellitus (0431-021)

Inclusion Criteria: * Patients with type 2 diabetes mellitus * Patient is not pregnant or breastfeeding * Male or female patient unlikely to conceive * Patient not on an antihyperglycemic drug Exclusion Criteria: * Patient has history of type 1 diabetes mellitus * Patient has history of ketoacidosis * Patient requires insulin within 8 weeks prior to start of study * Patient on weight loss program and is not in maintenance phase * Patient taking weight loss medication within 8 weeks prior to start of study * Patient on or likely to require = 14 days or repeated courses of corticosteroids * Patient taking immunosuppressive/immunomodulating medication * Patient taking digoxin or other cardiac medication * Patient has undergone surgical general anesthesia within 30 days prior to start of study * Patient taking investigational drug within 8 weeks prior to start of study * Patient is diagnosed with liver disease * Patient has chronic myopathy, progressive neurological/neuromuscular disorder * Patient has with severe cardiac conditions within the last 6 months * Patient is Human immunodeficiency virus (HIV) positive * Patient has hematological disorder * Patient has history of malignancy * Patient has history of alcohol or drug abuse within the past 3 years