A Study to Evaluate the Effect of Thymoglobulin and Reduced Doses of Steroids to Prevent Renal Transplant Rejection

Inclusion Criteria: * Adult living donor renal transplant recipient * Age greater than or equal to 18 * If female and of childbearing potential: a) must not be lactating; b) must have a negative serum B-human chorionic gonadotropin (HCG) test within 24 hours prior to Study Day 0 (Day of Transplant) and; c) must agree to practice an acceptable and reliable form of contraception during the study; and * Signed informed consent Exclusion Criteria: * Human Leukocyte Antibody (HLA) identical matched living donor transplant recipient * \> 2 previous transplants * Current panel reactive antibody (PRA) \> 20% * History of a positive cross-match with the donor * Active donor or recipient serology positive for human immunodeficiency virus (HIV), Hepatitis B virus (HBV) or Hepatitis C virus (HCV) * Loss of first kidney transplant in \< 1 year * History of noncompliance in clinical trial(s) * History of chronic CS or immunosuppressive use except for inhaled CS to treat asthma * Use of any investigational products during the 90 days prior to screening * Requirement for multiple organ transplant * Patient without a functioning urinary bladder prior to transplant (e.g. patients with self catheterization will be excluded) * Known contraindication to administration of rabbit antithymocyte globulin * Currently abusing drugs or alcohol * In the opinion of the investigator, at high risk for poor compliance * In the opinion of the investigator, has a significant medical or psychosocial problem or unstable disease state that warrants exclusion from the study. Examples of significant problems include, but are not limited to morbid obesity and severe cardiac disease.