Elsamitrucin (SPI 28090) for Relapsed or Refractory Non-Hodgkin's Lymphoma

Inclusion Criteria: * Relapsed or Refractory mantle cell lymphoma and/or CLL/SLL except Burkitt's, Burkitt's like or HIV-associated lymphoma * at least one prior cytotoxic chemotherapy regimens * measurable disease * adequate bone marrow, liver and kidney function * ECOG PS 0-2 Exclusion Criteria: * prior treatment with elsamitrucin * prior chemo, antibody or radiotherapy for NHL within 28 days prior to start to treatment * HIV positive or known AIDS syndrome * uncontrolled medical disease or psychiatric condition/s