A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-183)

Merck Sharp & Dohme LLC269 enrolled

Overview

The purpose of this study is to compare the safety and effectiveness of two approved drugs in the treatment of pain following dental surgery.

The duration of treatment is 24 hours.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

269

Conditions

Postoperative Pain

Interventions

MK0966, rofecoxibDRUG

Comparator: oxycodone with acetaminophen, placeboDRUG

Eligibility

Sex: ALLMin age: 16 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Impaction of a molar tooth requiring removal Exclusion Criteria: * Any known allergy to the study drugs

Outcomes

Primary Outcomes

Post-op dental pain over 6 hours as measured by pain intensity/relief scores, patient global assessment, and time to perceptible/meaningful pain relief.

Secondary Outcomes

Time to onset of analgesic effect, peak analgesic effect, and/or duration of analgesic effect over 24 hours.

Data from ClinicalTrials.gov

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