Interactions Between Cocaine and Ethanol and Disulfiram - 1

National Institute on Drug Abuse (NIDA)16 enrolled

Overview

The purpose of this study is to assess potential interactions between intravenous cocaine and ethanol and oral disulfiram.

This is a two-site, double blind, placebo-controlled inpatient study to determine the cardiovascular and psychiatric safety of alcohol use in cocaine-dependent subjects who had used cocaine after treatment with disulfiram.

Study Type

INTERVENTIONAL

Purpose

TREATMENT

Enrollment

Conditions

Interventions

DisulfiramDRUG

Eligibility

Sex: ALLMin age: 18 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Must meet DSM-4 criteria for cocaine abuse or dependence and are not seeking treatment. * Ability to verbalize understanding of consent form and provide written informed consent and verbalize willingness to complete study procedures; be able to comply with protocol requirements. Exclusion Criteria: * Please contact site for more information.

Locations (2)

UCLA Integrated Substance Abuse Program

Los Angeles, California, United States

University of Texas Hlth Sci Ctr San Ant

San Antonio, Texas, United States

Outcomes

Primary Outcomes

Safety assessments

Psychological effects

Data from ClinicalTrials.gov

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