Coenzyme Q10 in Relieving Treatment-Related Fatigue in Women With Breast Cancer

Inclusion Criteria: * Signed consent * Hg \> 11g/dl; supportive measures (erythropoietin, transfusion, iron therapy) should be utilized to assist with maintaining Hgb levels * Total cholesterol \> 160mg/dL. * Female with primary cancer diagnosis (breast) * Planned adjuvant chemotherapy (neoadjuvant chemotherapy is excluded) * KPS \> 60 * Bilirubin \< 1.5 x ULN * SGOT \< 2.5 x ULN * SGPT \< 2.5 x ULN Exclusion Criteria: * Recent involuntary weight loss (\> 5% of body weight in the past 3 months) * Statin therapy - current or planned during study. Below is a list of some commonly used statin drugs.(Note: This is a helpful guide, not a complete list.) * Atorvastatin (Lipitor) * Cerivastatin * Fluvastatin (Lescol) * Lovastatin (Mevacor, Altocor, Advicor) * Mevastatin * Pravastatin (Pravachol) * Rosuvastatin * Simvastatin (Zocor) * Current or planned use of the following medications for fatigue * Corticosteroids (intermittent use as part of chemotherapy regimen is allowed) * Amphetamines or other stimulants including methylphenidate (Ritalin)or modafinil (Provigil) * Patients diagnosed with uncontrolled hypertension * Breast cancer patients who are male * Pregnant women are excluded from participation in this study. A Serum pregnancy test is required within 1 week of registration if the patient is a woman of childbearing potential. * Anticoagulant therapy - current or planned during study (except for maintenance of catheter patency) * Patients with uncontrolled thyroid dysfunction