A Research Study for Patients With Metastatic Renal Cell Carcinoma

Inclusion Criteria: Patients must fulfill all of the following criteria to be eligible for study participation: * Age ≥ 18 years; * Histologically confirmed Renal Cell Carcinoma (RCC); * Metastatic disease, with measurable lesions according to the Response Evaluation Criteria in Solid Tumors (RECIST); * Failure of prior cytokine therapy; * Documented progressive disease; Exclusion Criteria: Patients are ineligible for entry if any of the following criteria are met: * Significant cardiac disease including congestive heart failure, history of myocardial infarction within one year, uncontrolled dysrhythmias, or poorly controlled angina * History of serious ventricular arrhythmia * Corrected QT interval (QTc) ≥ 500 msec * Known infection with Human Immunodeficiency Virus (HIV), Hepatitis B, or Hepatitis C; * Previous extensive radiotherapy involving ≥ 30% of bone marrow * Coexistent second malignancy or history of prior malignancy within previous 5 years