To test the effectiveness of an smoking cessation treatment for smokers who also drink alcohol heavily.
Heavy alcohol use frequently co-occurs with cigarette smoking and may impede smoking cessation. This clinical trial examined whether smoking cessation treatment that incorporates brief alcohol intervention can improve smoking cessation outcomes (7-day verified point prevalence abstinence) and reduce drinks consumed per week. Heavy drinkers seeking smoking cessation treatment were assigned by urn randomization to receive, along with 8-weeks of nicotine replacement therapy, either a 4-session standard smoking cessation treatment (ST, n = 119) or standard treatment of equal intensity that incorporated brief alcohol intervention (ST-BI, n = 117).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
236
Standard smoking cessation treatment with nicotine patch plus a brief alcohol-focused intervention
Behavioral smoking cessation counseling and nicotine patch.
Brown University
Providence, Rhode Island, United States
Smoking Abstinence at 26 Weeks
7 days of smoking abstinence confirmed biochemically at 26 week post quit attempt
Time frame: 26 weeks
Smoking Abstinence at 16 Weeks
7 days of smoking abstinence confirmed biochemically at 16 weeks
Time frame: 16 weeks
Smoking Abstinence at 8 Weeks
7 days of smoking abstinence confirmed biochemically at 8 weeks
Time frame: 8 weeks
Smoking Abstinence at 2 Weeks
7 days of smoking abstinence confirmed biochemically at 2 weeks
Time frame: 2 weeks
Alcohol Drinks Consumed Per Week Over a 2-week Period
Average number of standard alcoholic drinks consumed per week over each 2-week period across the 26 weeks of follow-up as assessed by the Timeline Followback Interview. Standard alcoholic drink is defined as 12 oz of beer, 5 oz of wine, or 1.5 ounces of liquor.
Time frame: At 2, 8, 16, and 26-week follow-ups
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