The Effects of Risperidone and Olanzapine on Thinking

US Department of Veterans Affairs

Overview

The goal of this research is to find ways to maximize the benefits of antipsychotic medications for cognition. Hypothesis: Risperidone and olanzapine will show greater benefits than conventional medications on assessments of social cognition, particularly affect perception and social perception.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Conditions

Schizophrenia Psychotic Disorders

Interventions

RisperidoneDRUG

OlanzapineDRUG

Eligibility

Sex: ALLMin age: 18 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnosed with schizophrenia disorder by a DSM IV. * Competent to sign informed consent * No history of poor response to Risperdal and Zyprexa * No organic brain disease Exclusion Criteria: * Mental retardation or any chronic medical illness which results in the patient not being appropriate for a switch to Risperdal or Zyprexa.

Locations (1)

VA Greater Los Angeles Healthcare System

Los Angeles, California, United States

Data from ClinicalTrials.gov

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