The study is a behavioral clinical trial of aerobic exercise to determine dose-response effects on risk for type 2 diabetes, fatness, fitness, blood cholesterol levels, and other cardiovascular risk factors in overweight elementary schoolchildren. The hypothesis is that the more exercise a child does, the more benefit he or she will gain in reducing the risk of diabetes and other cardiovascular diseases. An ancillary study examined effects on cognition and achievement.
The study is a behavioral clinical trial of aerobic exercise to determine dose-response effects on insulin response to the oral glucose tolerance test, body composition, fitness, lipid profile, inflammation and other metabolic syndrome components in overweight elementary schoolchildren. Blinded psychological assessments of cognition and achievement were obtained.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
222
Vigorous intermittent physical activity in group format conducted in research gymnasium after school by research staff. Heart rate monitors documented each child's average heart rate on a daily basis. Small incentives were offered for achieving goal of \>150 bpm average HR each day and attending at least 80% of sessions (4 days/week).
Georgia Prevention Institute, Medical College of Georgia
Augusta, Georgia, United States
Insulin area under the curve (oral glucose tolerance test)
Time frame: 10-15 weeks
Body composition (% body fat, visceral fat)
Time frame: 10-15 weeks
Aerobic fitness
Time frame: 10-15 weeks
Cognition (Executive function)
Time frame: 10-15 weeks
Glucose (oral glucose tolerance test)
Time frame: 10-15 weeks
Lipid profile
Time frame: 10-15 weeks
Inflammation (C-reactive protein, fibrinogen)
Time frame: 10-15 weeks
Blood pressure
Time frame: 10-15 weeks
Academic achievement
Time frame: 10-15 weeks
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