The purpose of this study is to determine whether daily supplementation of young children in Nepal with either zinc, iron-folic acid, or both can reduce mortality and morbidity. Young children in Nepal have numerous nutritional deficiencies and high rates of morbidity and mortality. Zinc and/or iron supplementation may be a cost-effective method for reducing these risks.
Mortality rates among preschool age children in Nepal and many other developing countries remain high despite significant progress made over the past 20 years. There remain significant nutritional deficiencies in these populations, especially important are vitamin and mineral deficiencies. Comparisons: In this study, we are comparing the morbidity and mortality experience for children 1-36 months of age randomized to one of four daily supplementation regimens: placebo, zinc alone, iron-folic acid alone, zinc + iron-folic acid.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
58,000
Johns Hopkins Bloomberg School of Public Health
Baltimore, Maryland, United States
Cornell University Division of Nutritional Sciences
Ithaca, New York, United States
Nepal Nutrition Intervention Project-Sarlahi
Kathmandu and Sarlahi District, Nepal
Death among children 1-36 months of age
Incidence rates of selected morbidities including diarrhea, dysentery, acute respiratory infections
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.