The purpose of this Phase II study is to evaluate the efficacy and safety of ispronicline (TC-1734-112) compared to placebo (inactive substance pill) in patients with age associated memory impairment (AAMI). AAMI is characterized as cognitive impairment including memory loss and poor concentration associated with aging.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
174
Pivotal Research Center
Mesa, Arizona, United States
Pivotal Research Center
Peoria, Arizona, United States
Radiant Research
Denver, Colorado, United States
To assess safety and tolerability of ispronicline vs. placebo in generally healthy elderly subjects with subjective and objective memory impairment meeting the generally accepted criteria for AAMI.
To assess effect, on cognition, of ispronicline vs. placebo in generally healthy elderly subjects with subjective and objective memory impairment meeting the generally accepted criteria for AAMI.
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Neuropsychiatric Research Center of SW Florida
Fort Meyers, Florida, United States
Meridien Research
Saint Petersberg, Florida, United States
Meridien Research
Tampa, Florida, United States
Northlake Medical Research Center
Decatur, Georgia, United States
Hartford Research
Florence, Kentucky, United States
Berman Center
Minneapolis, Minnesota, United States
Radiant Research
St Louis, Missouri, United States
...and 5 more locations