Laser-assisted intracytoplasmic sperm injection (ICSI) has been suggested as a more effective alterative to conventional ICSI when this method of insemination is indicated for patients undergoing in vitro fertilization (IVF). Laser-assisted ICSI differs from conventional ICSI in that a laser is used to drill a small hole through the hard outer coating surrounding an egg before the injection needle containing a single sperm is inserted into the egg. The hole eliminates compression of the egg that normally occurs with conventional ICSI, and thus may reduce the chance of damage. Laser-assisted ICSI is hypothesized to result in increased egg survival, and perhaps improved embryo quality, compared to conventional ICSI.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
60
Shady Grove Fertility Reproductive Science Center
Rockville, Maryland, United States
oocyte survival rate 1 day after ICSI
normal fertilization rate 1 day after ICSI
embryo cell numbers 2 and 3 days after ICSI
embryo fragmentation rates 2 and 3 days after ICSI
embryo compaction rate through day 7 after ICSI
blastocyst formation rate through day 7 after ICSI
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