Study to Assess the Safety and Efficacy of Imiquimod 5% Cream for the Treatment of Actinic Keratosis on the Arms and Hands

Inclusion Criteria: * 18 years of age * Have AK on arm or hand * Discontinuation of sun tanning and the use of tanning beds * Discontinuation of the use of moisturizers, body oils, over-the-counter retinol products and products containing alpha or beta hydroxy acid in the treatment and surrounding area * Withholding of the use of sunscreen in the treatment area for 24 hours prior to all study visits and for 8 hours before applying study cream * Postponement of the treatment of non-study AK lesions anywhere on the arm being treated until study participation is complete Exclusion Criteria: * Subjects must not have any evidence of systemic cancer or immunosuppression or other unstable health conditions * Participation in another clinical study * Have previously received treatment with imiquimod within the treatment area * Have squamous cell carcinoma (SCC), basal cell carcinoma (BCC), or other malignancy in the treatment or surrounding area that requires treatment